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Brianne Disabato, MD

Current Position
Assistant Professor of Psychiatry

University Roles
Medical Director, Psychiatry Clinic

Education and Training
BA: Biology & Anthropology, Washington University in St. Louis, 1998-2002

M.D: Mount Sinai School of Medicine, New York, New York, 2002-2006

Residency: Psychiatry, Washington University School of Medicine, 2006-2010

Major Awards
Resident of the Year Award, Washington Univesity School of Medicine, 2010

Howard Hughes Medical Institute Research Fellowship

Areas of Clinical Interest
Adult and Geriatric Psychiatric Disorders including Major Depressive Disorder, Anxiety Disorders, Schizophrenia, Bipolar Disorder


Areas of Research Interests
My research interests include geriatric illnesses; specifically, dementias such as Alzheimer's Dementia and Late-Life Depression. I am a clinical investigator at the Washington University School of Medicine Alzheimer's Dementia Research Center. Also, I am involved in late-life depression research using neuroimaging to evaluate treatment outcomes in geriatric depression.


Key Publications
Disabato BM, Sheline YI (2012 May 6). Biological Basis of Late Life Depression. Curr Psychiatry Rep.   Full Article ->

Cirrito JR, Disabato BM, Restivo JL, Verges DK, Goebel WD, Sathyan A, Hayreh D, D'Angelo G, Benzinger T, Yoon H, Kim J, Morris JC, Mintun MA, Sheline YI. Serotonin signaling is associated with lower amyloid-ß levels and plaques in transgenic mice and humans. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14968-73. PMID: 21873225

Disabato BM, Morris C, Hranilovich J, D'Angelo GM, Zhou G, Wu N, Doraiswamy PM, Sheline YI (2013 Jun 11). Comparison of Brain Structural Variables, Neuropsychological Factors, and Treatment Outcome in Early-Onset Versus Late-Onset Late-Life Depression. Am J Geriatr Psychiatry.   Full Article ->

Sheline YI, Disabato BM, Hranilovich J, Morris C, D'Angelo G, Pieper C, Toffanin T, Taylor WD, MacFall JR, Wilkins C, Barch DM, Welsh-Bohmer KA, Steffens DC, Krishnan RR, Doraiswamy PM (2012 Nov 1). Treatment course with antidepressant therapy in late-life depression. Am J Psychiatry. 169(11): 1185-93.  Full Article ->