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Sarah Hartz, MD, PhD

Current Position
Assistant Professor of Psychiatry

Education and Training
BA: Knox College, Galesburg, IL, 1996
PhD in Statistics: University of Illinois Urbana-Champaign, 2003
MD: University of Iowa 2005
Residency: Psychiatry, University of Iowa Hospitals and Clinics and Washington University/Barnes-Jewish Hospital, 2005-2009

Major Awards
-The George Winokur Award for Resident Research, First Prize, 2007
-National Council on Measurement in Education Educational Technology Applications Award, 2005
American Psychological Association Distinguished Dissertation, Division of Evaluation, Measurement and Statistics, 2003
-National Council on Measurement in Education Brenda H Lloyd Outstanding Dissertation Award, 2003
-Horace W. Norton Prize for the most outstanding thesis research in statistics, 2002
-Maurice Tatsuoka award for excellence in educational measurement, 2001

Areas of Clinical Interest
Substance dependence, bipolar disorder, schizophrenia


Areas of Research Interests
Psychiatric Genetics


Key Publications
Hartz SM, Pato CN, Medeiros H, Cavazos-Rehg P, Sobell JL, Knowles JA, Bierut LJ, Pato MT, Genomic Psychiatry Cohort Consortium (2014 Mar). Comorbidity of severe psychotic disorders with measures of substance use. JAMA Psychiatry. 71(3): 248-54.  Full Article ->

Hartz, SM, S Short, NL Saccone, R Culverhouse, L Chen, T Schwantes-An, H Coon, Y Han, SH Stephens, J Sun, X Chen, F Ducci, N Dueker, N Franceschini, J Frank, F Geller, D Guðbjartsson, N Hansel, C Jiang, K Keskitalo-Vuokko, J Liu, LP Lyytikäinen, M Michel, R Rawal, A Rosenberger, P Scheet, JR Shaffer, A Teumer, JR Thompson, J Vink, N Vogelzangs, A Wenzlaff, W Wheeler, X Xiangjun , BZ Yang, SH Aggen, A Balmforth, S Baumeister, T Beaty, S Bennett, A Bergen, H Boyd, U Broms, H Campbell, N Chatterjee, J Chen, YC Cheng, S Cichon, D Couper, F Cucca, D Dick, T Foroud, H Furberg, I Giegling, F Gu, A S Hall, J Hällfors, S Han, AM. Hartmann, C Hayward, K Heikkilä, JK. Hewitt, J Hottenga, M Jensen, P Jousilahti, M Kaakinen, S Kittner, B Konte, T Korhonen, MT Landi, T Laatikainen, M Leppert, SM. Levy, R Mathias, DW. McNeil, S Medland, G Montgomery, T Muley, T Murray, M Nauck, K North, M Pergadia, O Polasek, E Ramos, S Ripatti, A Risch, I Ruczinski, I Rudan, V Salomaa, D Schlessinger, U Styrkársdóttir, A Terracciano, M Uda, G Willemsen, X Wu, G Abecasis, K Barnes, H Bickeböller, E Boerwinkle, DI. Boomsma, N Caporaso, J Duan, HJ. Edenberg, C Francks, PV. Gejman, J Gelernter, HJ Grabe, H Hops, MR Jarvelin, V Jorma, M Kähönen, K. Kendler, T Lehtimäki, DF. Levinson, ML. Marazita, J Marchini, M Melbye, B Mitchell, JC. Murray, MM. Nöthen, BW. Penninx, O Raitakari, M Rietschel, D Rujescu, NJ Samani , AR. Sanders, A Schwartz, S Shete, J Shi, M Spitz, K Stefansson, G Swan, T Thorgeirsson, H Völzke, Q Wei, H.-E Wichmann, C Amos, N Breslau, D Cannon, M Ehringer, R Grucza, D Hatsukami, A Heath, E Johnson, J Kaprio, P Madden, N G. Martin, V Stevens, JA. Stitzel, RB. Weiss, P Kraft, LJ. Bierut. Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Archives of General Psychiatry, in press.

Hartz, SM, Eric Johnson, Nancy L. Saccone, Dorothy Hatsukami, Naomi Breslau, Laura J. Bierut (2011). Barrier to inclusion of African American subjects in genetic studies: engagement rather than participation. American Journal of Epidemiology. 174(3):336-44.  Full Article ->

Stephens SH, Hartz SM, Hoft NR, Saccone NL, Corley RC, Hewitt JK, Hopfer CJ, Breslau N, Coon H, Chen X, Ducci F, Dueker N, Franceschini N, Frank J, Han Y, Hansel NN, Jiang C, Korhonen T, Lind PA, Liu J, Lyytikäinen LP, Michel M, Shaffer JR, Short SE, Sun J, Teumer A, Thompson JR, Vogelzangs N, Vink JM, Wenzlaff A, Wheeler W, Yang BZ, Aggen SH, Balmforth AJ, Baumeister SE, Beaty TH, Benjamin DJ, Bergen AW, Broms U, Cesarini D, Chatterjee N, Chen J, Cheng YC, Cichon S, Couper D, Cucca F, Dick D, Foroud T, Furberg H, Giegling I, Gillespie NA, Gu F, Hall AS, Hällfors J, Han S, Hartmann AM, Heikkilä K, Hickie IB, Hottenga JJ, Jousilahti P, Kaakinen M, Kähönen M, Koellinger PD, Kittner S, Konte B, Landi MT, Laatikainen T, Leppert M, Levy SM, Mathias RA, McNeil DW, Medland SE, Montgomery GW, Murray T, Nauck M, North KE, Paré PD, Pergadia M, Ruczinski I, Salomaa V, Viikari J, Willemsen G, Barnes KC, Boerwinkle E, Boomsma DI, Caporaso N, Edenberg HJ, Francks C, Gelernter J, Grabe HJ, Hops H, Jarvelin MR, Johannesson M, Kendler KS, Lehtimäki T, Magnusson PK, Marazita ML, Marchini J, Mitchell BD, Nöthen MM, Penninx BW, Raitakari O, Rietschel M, Rujescu D, Samani NJ, Schwartz AG, Shete S, Spitz M, Swan GE, Völzke H, Veijola J, Wei Q, Amos C, Cannon DS, Grucza R, Hatsukami D, Heath A, Johnson EO, Kaprio J, Madden P, Martin NG, Stevens VL, Weiss RB, Kraft P, Bierut LJ, Ehringer MA (2013 Dec). Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. Genet Epidemiol. 37(8): 846-59.  Full Article ->

Hartz SM, Lin P, Edenberg HJ, Xuei X, Rochberg N, Saccone S, Berrettini W, Nelson E, Nurnberger J, Bierut LJ, Rice JP; NIMH Genetics Initiative Bipolar Disorder Consortium (2010). Genetic association of bipolar disorder with the ß3 nicotinic receptor subunit gene. Psychiatric Genetics. 21(2):77-84  Full Article ->

Hartz SM, Bierut LJ (2010 Mar). Genetics of addictions. Psychiatr Clin North Am. 33(1): 107-24.  Full Article ->


Funded Research Projects
NIDA(PI):Novel Use of GWAS for Improved Understanding of Nicotine Dependence

ICTS(PI):Return of Results in Genetic Studies