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Charles Conway, MD

Current Position
Professor of Psychiatry

University Roles
Director, Treatment Resistant Depression and Neurostimulation Clinic
Interventional Psychiatry Rotation Director

Education and Training
B.A., Biology; B.A., Psychology
St. Louis University, 1987

Medical Degree: University of Missouri, Columbia, 1995

Residency: General Psychiatry, Duke University Medical Center, 1999

Major Awards
-Ziskind-Somerfeld Research Award, Society of Biological Psychiatry (selected for Nagele 2015 publication for highest priority score during peer review) 2016
-NARSAD Independent Investigator Grant (Co-I) 2016
-Stanley Medical Research Institute Bipolar Research Award 2015
-Best Doctors in America, (Best Doctors, Inc.) 2006-2015
-Resident Mentor Award 2011 (chosen by residents), Washington University Department of Psychiatry
-NARSAD Young Investigator Award 2007
-St. Louis University Psych Dept. Resident Faculty Teaching Award (selected by residents) 2004,2007
-Exemplary Psychiatrist Award, National Alliance for the Mentally Ill (NAMI) 2004
-Selected for National Institute of Mental Health (NIMH) Summer Research Fellowship 2004
-St. Luke Award, Saint Louis University Hospital; (selected as a physician who 'Best lived out the Christian mission of St. Louis University Hospital') 2001
-Chief Resident, John Umstead Hospital, Duke University Psychiatry Residency 1998-1999
-Phi Beta Kappa 1986

Areas of Clinical Interest
mood disorders, treatment-resistant mood disorders, bipolar disorders


Areas of Research Interests
treatment-resistant depression (TRD) phenomenology, novel treatments for TRD, neuroimaging of mood disorders, bipolar disorders


Key Publications
Conway CR, Gebara MA, Walker MC, Lessov-Schlaggar CN, Janski AM, Chibnall JT, Cristancho P, Sheline YS, Gott BM, Svrakic DM. Clinical Characteristics and Management of Treatment-Resistant Depression. J Clin Psych, 2015; Nov; 76(11): 1569-70. PMID: 26646033.

Nagele P, Duma A, Kopec M, Gebara MA, Parsoei A, Walker M, Janski A, Panagopoulos VN, Cristancho P, Miller JP, Zorumski CF, Conway CR. Nitrous Oxide for Treatment-Resistant Major Depression: A Proof-of-Concept Trial. Biological Psychiatry. 2015; Jul 1; 78(1). PMID: 25577164.

Conway CR, Chibnall JT, Gebara MA, Price JL, Snyder AZ, Mintun MA, Craig AD, Cornell ME, Perantie DC, Giuffra LA, Bucholz RD, Sheline YI. Association of cerebral metabolic activity changes with vagus nerve stimulation antidepressant response in treatment-resistant depression. Brain Stimulation, 2013; 6(5): 788-97. PMCID: PMC3954813.

Aaronson ST, Carpenter L, Conway C, Lisanby S, Schwartz T, Moreno F, Dunner D, Lesem M, Thompson P, Husain M, Vine C, Banov M, Bernstein L, Lehman R, Brannon G, Keepers G, O’Reardon J, Rudolph R, Bunker M. Vagus Nerve Stimulation Therapy at Different Amounts of Electrical Charge for Treatment Resistant Depression. Brain Stimulation, 2013; 6(4):631-40. PMID: 23122916.

Conway CR, Chibnall JT, Gangwani S, Mintun MA, Price JL, Hershey T, Giuffra LA, Bucholz RD, Christensen JJ, Sheline YI. Pretreatment cerebral metabolic activity correlates with antidepressant efficacy of vagus nerve stimulation in treatment-resistant major depression: A potential marker for response? J Aff Disorders, 2012; 139(3):283-290 PMCID: PMC3598572.

Conway CR, Sheline YI, Chibnall JT, George MS, Fletcher JW, Mintun MA.
Cerebral Blood Flow Changes during Acute Vagus Nerve Stimulation for Depression.
Psychiatry Res: Neuroimaging, 2006; 146(2):179-184. PMID: 16510266.


Funded Research Projects
Inhaled Nitrous Oxide for Treatment-Resistant Depression: Optimizing Dosing Strategies

Nitrous Oxide for Bipolar Depression

Targeting Affective Circuits Using the N-methyl-D-Aspartate (NMDA) Antagonist Nitrous Oxide

Randomized, Double-Blind Evaluation of the Impact of a Pharmacogenomic Tool on Response to Treatment in Major Depressive Disorder Outpatients