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Li-Shiun Chen, MD

Current Position
Assistant Professor of Psychiatry

Education and Training
M.D., National Taiwan University, Taiwan, 1993
M.P.H., Johns Hopkins University, Maryland,1995
Sc.D., Johns Hopkins University, Maryland, 1998
Psychiatry Residency, Washington University/Barnes-Jewish Hospital, St. Louis, 2004

Major Awards
Eli Robins Award, Washington University Department of Psychiatry, 2004
APA Resident Research Award, 2004
World Congress of Psychiatric Genetics Travel Award, 2009

Areas of Clinical Interest
Schizophrenia, Mood Disorder, Addiction, Personality Disorder, Community Psychiatry, Telepsychiatry, Cancer Psychiatry

Areas of Research Interests
1. Pharmacogenetics, clinical treatment trials,
and personalized medicine
2. Genetics of smoking cessation and psychiatric disorders
3. Cross-population and longitudinal studies
4. Classification of psychiatric disorders.

More articles and abstracts at the National Library of Medicine

Key Publications
Chen LS, Baker TB, Piper ME, Breslau N, Cannon DS, Doheny KF, Gogarten SM, Johnson EO, Saccone NL, Wang JC, Weiss RB, Goate AM, Bierut LJ. Interplay of Genetic Risk Factors (CHRNA5-CHRNA3-CHRNB4) and Cessation Treatments in Smoking Cessation Success. American Journal of Psychiatry, 2012. (in press)

Chen LS, Saccone NL, Culverhouse RC, Bracci PM, Chen CH, Dueker N, Han Y, Huang H, Jin G, Kohno T, Ma JZ, Przybeck TR, Sanders AR, Smith JA, Sung YJ, Wenzlaff AS, Wu C, Yoon D, Chen YT, Cheng YC, Cho YS, David SP, Duan J, Eaton CB, Furberg H, Goate AM, Gu D, Hansen HM, Hartz S, Hu Z, Kim YJ, Kittner SJ, Levinson DF, Mosley TH, Payne TJ, Rao DC, Rice JP, Rice TK, Schwantes-An TH, Shete SS, Shi J, Spitz MR, Sun YV, Tsai FJ, Wang JC, Wrensch MR, Xian H, Gejman PV, He J, Hunt SC, Kardia SL, Li MD, Lin D, Mitchell BD, Park T, Schwartz AG, Shen H, Wiencke JK, Wu JY, Yokota J, Amos CI, Bierut LJ. Smoking and Genetic Risk Variation across Populations of European, Asian, and African-American Ancestry - A Meta-analysis of Chromosome 15q25. Genetic Epidemiology, 2012. (in press)

Chen LS, Johnson EO, Breslau N, Hatsukami D, Saccone NL, Grucza RA, Wang JC, Hinrichs AL, Fox L, Goate AM, Rice JP, Bierut LJ (2009 Oct). Interplay of Genetic Risk Factors and Parent Monitoring in Risk for Nicotine Dependence. Addiction. 104(10): 1731-1740.  Full Article ->

Chen LS, Rice TK, Thompson PA, Barch DM, Csernansky JG (2009 Jun). Familial aggregation of clinical and neurocognitive features in sibling pairs with and without schizophrenia. Schizophr Res. 111(1-3): 159-66.  Full Article ->

Chen LS, Eaton WW, Gallo JJ, Nestadt G, Crum RM (2000 Apr). Empirical examination of current depression categories in a population-based study: symptoms, course, and risk factors. Am J Psychiatry. 157(4): 573-80.  Full Article ->

Eaton WW, Neufeld K, Chen LS, Cai G (2000 Mar). A comparison of self-report and clinical diagnostic interviews for depression: diagnostic interview schedule and schedules for clinical assessment in neuropsychiatry in the Baltimore epidemiologic catchment area follow-up. Arch Gen Psychiatry. 57(3): 217-22.  Full Article ->

Funded Research Projects
NIDA (PI): Genetic and Environmental Risks for Smoking Characteristics and Cessation