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John Constantino, MD

Current Position
Blanche F. Ittleson Professor of Psychiatry and Pediatrics

University Roles
Director, William Greenleaf Eliot Division of Child & Adolescent Psychiatry
Director, Intellectual and Developmental Disability Research Center

Education and Training
B.A.: Cornell University, Ithaca, New York, 1984
Medical Degree: Washington University School of Medicine, St. Louis, Missouri, 1988
Residency: Pediatrics, Albert Einstein College of Medicine, Bronx, New York, 1990
Residency: Psychiatry, Albert Einstein College of Medicine, Bronx, New York, 1992
Fellowship: Child Psychiatry, Albert Einstein College of Medicine, Bronx, New York, 1993
Research Fellow: Psychiatric Epidemiology, Washington University School of Medicine, St. Louis, Missouri, 1996

Major Awards
Listed in Best Doctors in America, 2002-present (Best Doctors, Inc) & Best Doctors of St. Louis, 2009-present (St. Louis Magazine)
Gubernational Appointment to the Mental Health Commission, State of Missouri, 2003-2007
Distinguished Service Teaching Award (Clinical Teacher of the Year) WUSM, 2003
Child Advocate of the Year, St. Louis Area Council on Child Abuse and Neglect, 2007
Guardian Angel Award, Family Support Network, St. Louis Missouri, 2008
Irving Philips Award for Prevention (Health Promotion and Prevention Committee), American Academy of Child and Adolescent Psychiatry, 2014

Areas of Clinical Interest
Disorders of social development in children (infancy through early adulthood) including autism, abnormally aggressive behavior, personality disorder; psychiatric complications of neurodevelopmental disorders; treatment-refractory child psychiatric conditions.


Areas of Research Interests
1) the influence of genetic and environmental influences on childhood social development;
2) the genetic structure of autism spectrum disorders;
3) the prevention of child maltreatment and its consequences
4) the intergenerational transmission of attachment;
5) the development of rapid, quantitative methods for phenotypic characterization of autism and related developmental disorders;


More articles and abstracts at the National Library of Medicine

Key Publications
Constantino, JN, Charman T. Diagnosis of Autism Spectrum Disorder: Reconciling the syndrome, its diverse origins, and variation-in-expression. The Lancet Neurology, in press.

Marrus N, Glowinski AL, Jacob T, Klin A, Jones W, Drain CE, Holzhauer KE, Hariprasad V, Fitzgerald RT, Mortenson EL, Sant SM, Cole L, Siegel SA, Zhang Y, Agrawal A, Heath AC, Constantino JN (2015 Feb 11). Rapid video-referenced ratings of reciprocal social behavior in toddlers: a twin study. J Child Psychol Psychiatry.   Full Article ->

Presnall N, Webster-Stratton CH, Constantino JN (2014 Aug). Parent training: equivalent improvement in externalizing behavior for children with and without familial risk. J Am Acad Child Adolesc Psychiatry. 53(8): 879-87.  Full Article ->

Constantino JN (2014 Sep 17). Recurrence rates in autism spectrum disorders. JAMA. 312(11): 1154-5.  Full Article ->

Constantino JN, Zhang Y, Frazier T, Abbacchi AM, Law P (2010 Nov). Sibling recurrence and the genetic epidemiology of autism. Am J Psychiatry. 167(11): 1349-56.  Full Article ->

Constantino JN, Todd RD (2003 May). Autistic traits in the general population: a twin study. Arch Gen Psychiatry. 60(5): 524-30.  Full Article ->


Funded Research Projects
CDC (PI): Metropolitan St. Louis Autism & Developmental Disabilities Surveillance & Epidemiology

NIMH (Site PI): ACE Network: A Comprehensive Approach to the Identification of Autism Susceptibility Genes

NICHD (PI): Washington University Intellectual and Developmental Disabilities Research Center

St. Louis County Children’s Service Fund (PI): Comprehensive Approach to Unmet Mental Health Needs of Preschool Children in Foster Care, Phase 1

NICHD (PI): Early Quantitative Characterization of Reciprocal Social Behavior