Family Therapy and Fluoxetine in the Treatment of Adolescent Anorexia Nervosa
Reference Number: 201106179
WHAT IS THE PURPOSE OF THE STUDY?
This study will compare the short & long term effectiveness of Behavioral Family Therapy (BFT) and Systems Family Therapy (SFT) as treatments for adolescents with anorexia nervosa (AN). It will also compare fluoxetine (Prozac) to placebo (inactive substance) to see if it is helpful in addition to family therapies.
WHO IS NEEDED?
Volunteers must be 12-18 years old.
Volunteers must meet diagnostic criteria for anorexia nervosa (AN)
Volunteers must have parents that are willing to participate in the study with them.
WHAT IS INVOLVED IF I PARTICIPATE?
Duration: Participation is 21 months. There will be 16 family therapy visits over the course of 9 months (each about 1 hour) and 4 assessment visits (each 2-3 hours). There will also be lab visits lasting 30min to 1 hour.
Tests/Procedures: Measurement of height and weight, medical motoring by a study psychiatrist, laboratory tests, and administration of either fluoxetine or placebo
Risks: Risks will be discussed with volunteers as part of the informed consent process.
Benefits: It is possible that the child's physical and psychological well-being may be improved by the therapy offered in this study. Family therapy sessions, medication, and medical monitoring are provided at no charge.
Compensation: Up to $75 is provided for time and effort.
WHO IS THE PRINCIPAL INVESTIGATOR (DOCTOR)?
Denise E. Wilfley, Ph.D.
WHERE WILL THE STUDY TAKE PLACE?
Washington University School of Medicine, Storz Building
4570 Children's Place
St. Louis, MO 63110
Emily White, Project Coordinator