TIME AND PRICE ESTIMATES
TIME ESTIMATES
  1. Handling and tail marking = 10 minutes per mouse
  2. Basic sensorimotor battery (in minutes)
    • inverted screen = 5
    • platform = 5
    • ledge = 5
    • walking initiation = 5
    • slips = 5
    • Irwin assay = 10
    • walking path analysis = 10

    TOTAL of 7 SM TESTS = 45 minutes per mouse
    FIRST 4 SM TESTS ONLY (inverted screen, platform, ledge, walking init.) = 20 minutes per mouse

  3. Locomotion = 75 minutes per 4 mice
  4. Thermal paw = 180 minutes per 6 mice
  5. Rotorod = 2 hours per 4 mice
  6. Plus maze = 20 minutes per mouse (w/restraint 30 minutes a mouse)
  7. Acoustic startle/Prepulse inhibition = 30 minutes per 2 mice
  8. Fear conditioning = 60 min per 2 mice
  9. Cued and place Morris swim maze = 180 minutes per mouse

These time estimates do not include time spent per mouse for daily equipment set up, equipment break down, or data entry. The time spent in these endeavors is somewhat independent of the time estimates for each mouse and somewhat dependent on how much data is generated per test, if the test is automated or not, how many days the test will be performed, what needs to be done to the equipment between tests, how difficult is it to set up or breakdown the equipment.

PRICE ESTIMATES (as of 12/27/99)
Estimate for each test (most costs based on $40 an hour) for 30 mice.

BASIC SENSORIMOTOR BATTERY (for tests a-d only)

  • 30 mice x 20 minutes a mouse = 10 hours x $40 an hour = $400
  • Set-up and data entry = 2 hours = $80
  • Total = $480

LOCOMOTION/OPEN FIELD

  • 30 mice x 75 minutes per 4 mice = 8 sets of 4 mice x 75 minutes = 10 hours x $40 an hour = $400
  • Set-up and data entry = 3 hours = $120
  • Total = $520

THERMAL PAW PAIN TEST

  • 30 mice x 180 minutes per 6 mice = 5 sets of 6 mice x 180 minutes = 15 hours x $40 = $600
  • Set up and data entry = 3 hours = $120
  • Total = $720

ROTOROD (COORDINATION & MOTOR LEARNING)

  • 30 mice x 60 minutes per 4 mice = 8 sets of 4 mice runs x 2 hours = 16 hours x $40 an hour = $640 **two week test**
  • Set up and data entry = 7 hours = $280
  • Total = $920

PLUS MAZE ANXIETY 1 DAY TEST

  • 30 mice x 20 minutes per mice = 10 hours x $40 an hour = $400
  • Set up and data entry = 2 hours = $80
  • Total = $480

- OR -

PLUS MAZE ANXIETY 3 DAY TEST

  • 30 mice x 1 hour per mouse = 30 hours x $40 an hour = $1200
  • Set up and data entry = 6 hours = $240
  • Total = $1440

- AND/OR -

3 DAY PLUS MAZE RESTRAINT 3 DAY TEST

  • 30 mice x 90 minutes per mouse = 45 hours x 40 an hour = $1800
  • Set up and data entry = 6 hours = $240
  • Total = $2040

STARTLE/PREPULSE INHIBITION TEST OF ANXIETY AND SENSORIMOTOR GATING

  • 30 mice x 30 minutes per 2 mice = 15 sets of mice x 30 minutes = 7.5 hours x 40 an hour = $300
  • Set up and data entry = 4 hours = $160
  • Total = $460

FEAR CONDITIONING LEARNING TEST

  • 30 mice x 60 minutes per 2 mice = 15 sets of mice x 60 minutes = 15 hours x $40 an hour = $600
  • Set up and data entry = 4 hours = $180
  • Total = $780

MORRIS SWIM MAZE SPATIAL MEMORY ($25 an hour)<

**Two Week Test**
  • 30 mice x 180 minutes per mouse = 90 hour x $25 an hour = $2250
  • Set up and data entry = 10 hours = $250
  • Total = $2500
OTHER EXPENSES

ACCLIMATION OF MICE TO ANIMAL HANDLING AND TAIL MARKING

  • 30 mice x 10 minutes per mouse = 6 hours x $40 an hour = $240

ANIMAL PER DIEM

  • $0.53 a cage for group-housed mice and $0.33 for single-housed mice for entire length of stay.
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