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Li-Shiun Chen, MD
Current
Position
Instructor in Psychiatry
Education and Training
M.D.: National Taiwan University, Taiwan, 1993
M.P.H.:Johns Hopkins University, Maryland,1995
Sc.D.:Johns Hopkins University, Maryland, 1998
Residencyt: Psychiatry, Washington University/Barnes-Jewish Hospital, St. Louis, 2004
Major Awards
Eli Robins Award, Washington University Department of Psychiatry
APA Resident Research Award
Areas of Clinical Interest
Schizophrenia, Mood Disorders, Substabce Dependence, Personality Disorders, Community Psychiatry
Areas of Research Interests
1.Genetic studies of psychiatric disorders and substance dependence.
2.Genetics of cognition, brain structural and functional studies.
3.Psychiatric Epidemiology and longitudinal studies.
4.Classification of psychiatric disorders.
Key Publications
Crum RM, Chan Y-F, Chen LS, Storr CL, Anthony JC. Incidence rates and risk factors for alcohol dependence among adults: prospective data from the Baltimore ECA follow-up survey, 1981-1996. Journal of Studies on Alcohol 66(6): 795-805, 2005.
Chen LS, Eaton WW, Gallo JJ, Nestadt G, Crum RM. Empirical examination of current categories of depression in a population -based study: symptoms, course and risk factors. American Journal of Psychiatry 157(4): 573-80, 2000.
Chen LS, Eaton WW, Gallo JJ, Nestadt G. Understanding the heterogeneity of depression through the triad of symptom, course and risk factors: A longitudinal population-based study. Journal of Affective Disorders 59(1): 1-11, 2000.
Chen LS, Anthony JC, Crum RM. Perceived cognitive competence, depressive symptoms and the incidence of alcohol-related problems in urban school children. Journal of Child & Adolescent Substance Abuse 8(4): 108-118, 1999.
Lyketsos CG, Chen LS, Anthony JC. Cognitive decline in adulthood: a 12-year follow-up of the Baltimore Epidemiologic Catchment Area Study. American Journal of Psychiatry 156(1): 58-65, 1999.
Stine OC, McMahon FJ, Chen LS, Xu J, Meyers DA, MacKinnon DF, Simpson S, McInnis MG, Rice JP, Goate A, Reich T, Edenberg HJ, Foroud T, Nurberger, Jr. JI, Detera-Wadleigh SD, Goldin LR, Guroff J, Gershon ES, Blehar MC, DePaulo JR. Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: chromosomes 2, 11, 13, 14 and X. American Journal of Medical Genetics 74: 263-269, 1997.
Funded Research Projects
Global Research Awards for Nicotine Dependence(PI):Nicotine Dependence: Synthesizing Genetic and Environmental Risks
NHGRI(Key Personnel):Study of Addiction: Genetics and Environment
NIMH(Key Personnel):Mapping Abnormal Neurodevelopment in Schizophrenia