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Gabriel de Erausquin, MD, PhD

Gabriel de Erausquin, MD, PhD Current Position
Associate Professor of Psychiatry and Neurology

University Roles
Neuromodulation in Neuropsychiatry. Repetitive Transcranial Magnetic Stimulation and Deep Brain Stimulation.
Neurology-Psychiatry Outpatient Consultation.
BJC Behavioral Health. Neuropsychiatry Clinic.

Education and Training
Medical Degree: School of Medicine, Universidad de Buenos Aires, Argentina, 1986
Ph.D.: Behavioral Pharmacology, School of Medicine, Universidad de Buenos Aires, Argentina, 1990
Residency: Psychiatry, Yale University School of Medicine, New Haven, Connecticut, 1995
Research Fellowship: Biochemical Brain Imaging, Yale University School of Medicine, New Haven, Connecticut, 1995
Residency: Neurology, Washington University School of Medicine, St. Louis, Missouri, 1998
Research Fellowship: Neurology, Washington University School of Medicine, St. Louis, Missouri, 1998
Fellowship: Movement Disorders, Washington University School of Medicine, St. Louis, Missouri, 2003

Major Awards
NARSAD Klerman Award, 2008.
Young Investigator Award, National Alliance for Research in Schizophrenia and Depression, 2004 and 2007.
Distinguished Faculty Award, American Association of Chairs of Psychiatry, 2002
Joint Junior Faculty Award, Parkinson Disease Foundation and United Parkinson Foundation, 1998
S. Weir Mitchell Award, American Academy of Neurology, for research paper: Embryonic dopaminergic neurons are selectively susceptible to AMPA induced neurotoxicity: a mechanism for attrition of transplants in fetal mensencephalon, 1998
Young Investigator Award, International Conference on Schizophrenia Research, for research paper: AMPA induced neurotoxicity in the ventral tegmental area, a neurodevelopmental model of the physiopathology of schizophrenia, 1995
APA/Dista Products Resident Research Award, American Psychiatric Association, for research paper: AMPA-induced destabilization of [C++] homeostasis in dopaminergic neurons in vitro, 1993
Accesit Award "SEMCOSIN", Best Presentation in Neurosciences, Annual Meeting of Sociedad Argentina de Neurociencias, 1989

Areas of Clinical Interest
Clinical interests - Schizophrenia, psychotic disorders. Parkinson's disease, movement disorders. Neuromodulation. Neuropsychiatry.


  

Areas of Research Interests
Mechanism of dopaminergic neuronal death in Parkinson's disease and in transplants of embryonic mesencephalon.

Selective susceptibility of dopaminergic neurons to excitotoxicity during development.Role in pathophysiology of schizophrenia.

Imaging in schizophrenia.

Neuromodulation treatments in neuropsychiatry.


Key Publications
Zorumski CF, de Erausquin G, Dokucu M, Svrakic D, Garcia K, Jarvis M. Brain stimulation and the treatment of refractory psychiatric disorders. Mo Med. 2008 Jan-Feb;105(1):57-61.  Full Article ->

Tabbal S, Revilla FJ, Mink JW, Rich KM, de Erausquin GA, Wernle AR, Schneider Gibson P, Perlmutter JS, Dowling JL. Low risk of major surgical complications with restricted intraoperative physiologic mapping in bilateral subthalamic nucleus stimulation for Parkinson's disease. Journal of Neurosurgery, 2004 (Submitted)  Full Article ->

de Erausquin GA.Transactivation of cell death signals by glutamate transmission in dopaminergic neurons.Crit Rev Neurobiol. 2004;16(1-2):107-19.  Full Article ->

Dorsey DA, Soriano M, Masciotra L, Dikranian K, Garcia Verdugo JM, Faddis B, de Erausquin GA. Ultrastructural characterization of a new mechanism of cell death in embryonic dopaminergic neurons. Brain Research, Molecular Brain Research, 2004 (Submitted)  Full Article ->

Anastasia A, de Erausquin GA, Wojnacki J, Mascó DH. Protection of dopaminergic neurons by electroconvulsive shock in an animal model of Parkinson's disease.J Neurochem. 2007 Nov;103(4):1542-52.  Full Article ->

Mamah D, Wang L, Barch D, de Erausquin GA, Gado M, Csernansky JG.Structural analysis of the basal ganglia in schizophrenia.Schizophr Res. 2007 Jan;89(1-3):59-71. Epub 2006 Oct 30.  Full Article ->


Funded Research Projects
Philip Morris USA, Inc.(PI):Genetic Studies of Susceptibility to Nicotine Dependence in a Special Population of Antipsychotic-naive Patients with Schizophrenia
NIMH(PI):Genetics of Parkinsonism in a Special Population of Untreated Schizophrenia
NARSAD(PI):Imaging of Dopaminergic Networks in a Unique Population of Untreated Patients with Schizophrenia
Fogarty International Center(PI):Investigation on the Movement Abnormalities & Genetics of Schizophrenia (IMAGeS)