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Laura Jean Bierut, MD
Current
Position
Professor of Psychiatry
Education and Training
B.A.: Harvard Radcliffe College, Cambridge, Massachusetts, 1982
Medical Degree: Washington University, St. Louis, Missouri, 1987
Residency: Psychiatry, Washington University/Barnes Hospital, St. Louis, Missouri, 1991
Major Awards
Sidney I. Schwab Prize in Psychiatry
Washington University Book Award
International Brain Research Organization Award
Washington University Alumni Faculty Award
Areas of Clinical Interest
Alcohol, nicotine, marijuana, cocaine, substance dependence, major depressive disorder, bipolar disorder
Areas of Research Interests
Genetic studies of psychiatric illnesses
Genetic Studies of alcoholism, nicotine and substance dependence
Key Publications
Bierut LJ, Madden PAF, Breslau N, Johnson EO, Hatsukami D, Pomerleau OF, Swan GE, Rutter J, Bertelsen S, Fox L, Fugman D, Goate AM, Hinrichs AL, Konvicka K, Martin N, Montgomery G, Saccone NL, Saccone SF, Wang JC, Chase GA, Rice JP, Ballinger DG. Novel genes identified in a high density genome wide association study for nicotine dependence. Human Molecular Genetics 16:24-35, 2007. Full Article ->
Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, Madden PAF, Breslau N, Johnson EO, Hatsukami D, Pomerleau O, Swan GE, Goate AM, Rutter J, Bertelsen S, Fox L, Fugman D, Martin NG, Montgomery GW, Wang JC, Ballinger DG, Rice JP, Bierut LJ. Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Human Molecular Genetics 16(1):36-49, 2007. Full Article ->
Bierut LJ. Editorial: Genetic variation that contributes to nicotine dependence. In review Pharmacogenomics 8(8), 2007. Full Article ->
Bierut LJ, Cubells JF, Iacono W, Li MD, Madden PAF, Nelson EC, Pollock JD, Rutter JL, Swan GE, Vanyukov M, Bergen A, Caporaso N. Letter to the Editor: Genetic Research and Smoking Behavior. Journal of the American Medical Association 297(8):809, 2007. Full Article ->
Berrettini W, Bierut L, Crowley TJ, Cubells J, Frascella J, Gelernter J, Hewitt JK, Kreek MJ, Lachman H, Leppert M, Li MD, Madden P, Miner C, Pollock JD, Pomerleau O, Rice JP, Rutter JL, Shurtleff D, Swan GE, Tischfield J, Tsuang M, Uhl GR, Vanyukov M, Volkow ND, Wanke K: Letters to the Editor: Setting Priorities for Genomic Research. Science 2004; 304:1445-1446. Full Article ->
Funded Research Projects
NIAAA (SUNY)(PI):Collaborative Study on the Genetics of Alcoholism
NCI(PI):The Collaborative Genetic Study of Nicotine Dependence
NIMH(Key Personnel):NIMH Center for Collaborative Genetic Studies - Data Analysis
NIDA(PI):Case Control Candidate Gene Study of Addiction
NIDA(PI):Human Genetics of Addiction: A Study of Common and Specific Factors
NHGRI(PI):Study of Addiction: Genetics and Environment