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Tony Hinrichs, PhD
Current
Position
Research Assistant Professor of Psychiatry
Education and Training
B.S. Mathematics and Computer Science, Rose-Hulman Institute of Technology, 1993
M.A. Mathematics, Washington University, 1996
Ph.D. Mathematics, Washington University, 1998
Areas of Research Interests
My research focuses on methodology related to the genetic epidemiology of psychiatric disorders. In particular, I am developing methods to analyze large scale genotyping data in pedigrees for traits which have non-normal distributions. I am also examining methods of genetic analysis for individuals of mixed ancestry.
Key Publications
Hinrichs A, Lin JH, Reich T, Bierut L, Suarez BK (1999). Markov chain Monte Carlo linkage analysis of a complex qualitative phenotype. Genet Epidemiol. 17 Suppl 1S615-20. Full Article ->
Hinrichs AL, Suarez BK (2005). Genotyping errors, pedigree errors, and missing data. Genet Epidemiol. 29 Suppl 1S120-4. Full Article ->
Hinrichs AL, Wang JC, Bufe B, Kwon JM, Budde J, Allen R, Bertelsen S, Evans W, Dick D, Rice J, Foroud T, Nurnberger J, Tischfield JA, Kuperman S, Crowe R, Hesselbrock V, Schuckit M, Almasy L, Porjesz B, Edenberg HJ, Begleiter H, Meyerhof W, Bierut LJ, Goate AM (2006 Jan). Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. Am J Hum Genet. 78(1): 103-11. Full Article ->
Hinrichs AL, Bertelsen S, Bierut LJ, Dunn G, Jin CH, Kauwe JS, Suarez BK (2005 Dec 30). Multipoint identity-by-descent computations for single-point polymorphism and microsatellite maps. BMC Genet. 6 Suppl 1S34. Full Article ->
Hinrichs AL, Culverhouse R, Jin CH, Suarez BK (2007). Linkage and association analyses of principal components in expression data. BMC Proc. 1 Suppl 1S46. Full Article ->
Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, Madden PA, Breslau N, Johnson EO, Hatsukami D, Pomerleau O, Swan GE, Goate AM, Rutter J, Bertelsen S, Fox L, Fugman D, Martin NG, Montgomery GW, Wang JC, Ballinger DG, Rice JP, Bierut LJ (2007 Jan 1). Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet. 16(1): 36-49. Full Article ->
Funded Research Projects
NIAAA (SUNY)(Key Personnel):Collaborative Study on the Genetics of Alcoholism
NCI(Key Personnel):The Collaborative Genetic Study of Nicotine Dependence
NIA(Key Personnel):Genomic Search for Susceptibility to Alzheimer's Disease
NIMH(Key Personnel):Development of Antisocial Behavior in Early Adulthood
NIAAA(PI):Statistical Methods for the Genetics of Alcoholism
NIDA(Key Personnel):Case Control Candidate Gene Study of Addiction
Fidelity Foundation(Key Personnel):Pittsburgh Compound B: A Quantitative Endophenotype for Genetic Studies of AD Risk
NIMH(Key Personnel):Risk Genes for Late-Life Depression after Hip Fracture