This study was designed by Dr. John Newcomer, MD, in response to a need for more information about the effects in children of a type of medication called atypical or second-generation antipyschotics. Second-generation antipsychotic medications are most often used in adults to treat certain emotional and mental problems. They're called atypical because they cause less of the "typical" nervous system side effects of the older, first-generation antipsychotic medications. These medications are being used more and more often in children to treat emotional and mental problems, although these uses are not currently approved by the FDA. Doctors and scientists want to learn more about the use of these medications in children, including how children's bodies respond to them. For this study we are interested in learning how these medications might affect three things: weight gain, risk for diabetes, and cholesterol problems. The specific second-generation antipsychotic medications we are studying are Abilify (aripiprazole), Zyprexa (olanzapine), and Risperdal (risperidone).
Our study includes children who have been diagnosed by their doctor with various problems that can result in increased aggressiveness. Your child's doctor may have suggested that your child start on one of these medications. Joining our study will mean that your child will take one of these medications and receive extra medical care and attention for at least three months. Your child will be cared for and monitored by a team of doctors, therapists, and nurses who will be in close contact with your child's doctor. This study's goal is not only to learn new information but also to care for your child while doing so.
You will be paid up to $780 in gift certificates to stores and local attractions, depending upon how much of the study you complete. Naturally, we hope you complete the entire study because that will provide us with the best information.
Read on for information about children in research
or click here to download a printable, foldable Adobe Acrobat version of our informational booklet.
Our experience with the study: My son was involved with the pilot study on Metabolic Effects of Antipsychotic Medications and I was very amazed by his total cooperation and the outcome results. My youngest son has a medical diagnosis of autism and his cholesterol and triglyceride levels were very high. We were unaware of this and took immediate action to control the levels. We continue to monitor this, as to not endanger his overall health. My son was extremely cooperative in the pilot study. Many people thought that his cooperation could be questionable, but he proved us all wrong. I am so thankful that this avenue is being studied, because it is very important to manage our children's OVERALL health.
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